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Symbol
Name
ID
Mmp21
matrix metallopeptidase 21
MGI:2664387
Phenotype annotations related to cardiovascular system
Darker colors indicate more annotations
Human Phenotypes
Dextrocardia
Situs inversus totalis
Mesocardia
Left atrial isomerism
Right atrial isomerism
Atrial septal defect
Patent foramen ovale
Common atrium
Ventricular septal defect
Atrioventricular canal defect
Complete atrioventricular canal defect
Unbalanced atrioventricular canal defect
Subvalvular aortic stenosis
Single ventricle
Mitral atresia
Double outlet right ventricle
Transposition of the great arteries
Dextrotransposition of the great arteries
Cardiomegaly
Hypoplastic left heart
Right aortic arch
Hypoplastic aortic arch
Coarctation of aorta
Pulmonary artery atresia
Total anomalous pulmonary venous return
Interrupted inferior vena cava with azygous continuation
Bilateral superior vena cava
Left superior vena cava draining to coronary sinus
Patent ductus arteriosus
Mitral stenosis
Pulmonic stenosis
Asplenia
Ectopia of the spleen
Polysplenia
Disease(s) Associated with MMP21
visceral heterotaxy

Mouse Phenotypes
double outlet right ventricle
double outlet right ventricle with atrioventricular septal defect
double outlet right ventricle, Taussig bing type
transposition of great arteries
d-loop transposition of the great arteries
tricuspid valve atresia
atrioventricular septal defect
ventricular septal defect
heart right ventricle hypoplasia
Availability Mouse Genotype
Mmp21b2b873Clo/Mmp21b2b873Clo
Mmp21b2b2458Clo/Mmp21b2b2458Clo

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory